Sperm concentration, hyaluronic acid-binding capacity, aneuploidy and persistent histones in testicular cancer

Sperm concentration, hyaluronic acid binding capacity, aneuploidy and persistent histones

Sperm concentration, hyaluronic acid-binding capacity, aneuploidy and persistent histones in testicular cancer.

STUDY QUESTION Are the quantitative and qualitative characteristics of semen samples of patients with testicular cancer (TC), prior to anticancer therapy, different from infertile oligozoospermic (IO) and normozoospermic (NZ) age-matched men? SUMMARY ANSWER Sperm concentration in TC patients was significantly decreased with no difference in estimated numerical chromosome aberrations and nucle...

Relation Between Sperm Binding Ability to Hyaluronic Acid With Protamine Deficiency and DNAFragmentation

Purpose: The best sperm selection by its binding ability to hyaluronic acid for ICSI and assessment of correlation between sperm binding ability to hyaluronic acid with sperm parameters, protamine deficiency and DNA fragmentation. Materials and Methods: Semen samples collected from 55 infertile couples referring to ?? Fertility and Infertility center were collected during this study. Semen ana...

Sperm aneuploidy frequencies analysed before and after chemotherapy in testicular cancer and Hodgkin's lymphoma patients.

BACKGROUND Multicolour fluorescent in situ hybridization was utilized to detect sperm aneuploidy for chromosomes 13, 21, X and Y in testicular cancer and Hodgkin's lymphoma chemotherapy patients. METHODS Aneuploidy was assessed before, and 6, 12 and/or 18-24 months after, the initiation of chemotherapy, and compared with age matched controls. 635 396 sperm were scored blindly with 5000 sperm/pa...

Concentration of hyaluronic acid in synovial fluid.

ISOHE (1) HAS DESCRIBED a color reaction produced by the addition of alcoholic carbazole to uronic acids previously heated in 87% sulfuric acid. The purpose of the present report is to apply a modification of this method to the determination of hyaluronic acid in synovial fluid. The concentration of mucin in synovial fluid has been determined by the turbidity of the mucin clot (2) or by the che...